Pseudomonas Genome Database: A database for Pseudomonas aeruginosa and other Pseudomonas species genomes Pseudomonas Genome Database and PseudoCAP

NEWS

May 15, 2009

8 new annotation updates for P. aeruginosa PAO1

New PseudoCyc entry: Carnitine Catabolism to Glycine Betaine.

Fixed broken link to Pseudomonas Orthologous Groups (POGs) on gene cards.

Fixed formatting of text on FAQs page.

May 1, 2009

92 new updates to P.aeruginosa PAO1, PA14, LESB58, and PA7 genome annotations.

New search features added to advanced search, including limiting a search by gene size.

New Pseudomonas Genome Database publication. Please cite the article by Winsor et al. (2009; PMID:18978025) and not the web site URL.

Genes that are annotated as encoding for virulence factors have new details and external links.

Known drug target information is now available.

Fixed a bug that was causing a search of "All general fields" from a simple search form to fail.

PseudoCyc updated and capabilities expanded.

(More...)


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Pseudomonas aeruginosa is a versatile Gram-negative bacterium that grows in soil, coastal marine habitats, and on plant and animal tissues. People with cystic fibrosis, burn victims, and other patients in intensive care units are particularly at risk of disease resulting from P. aeruginosa infection. The complete sequence of the genome of P. aeruginosa strain PAO1 was published in Nature in the year 2000 and was noted for its large size and diverse metabolic capacity. The genome annotation is now being continually updated and the database functionality is being expanded to facilitate accelerated discovery of P. aeruginosa drug targets and vaccine candidates. This effort is being co-ordinated by Dr. Fiona Brinkman at Simon Fraser University and Dr. Bob Hancock at the University of British Columbia with database development led by Geoff Winsor of the Brinkman group. Funding for this work is gratefully provided by Cystic Fibrosis Foundation Therapeutics Inc., a non-profit drug discovery and development affiliate of the Cystic Fibrosis Foundation. The current annotation is updated using recent research literature and peer-reviewed submissions by a worldwide community of PseudoCAP participating researchers. If you are interested in participating, we invite you to get involved. Note that as of 2005, this database now also provides data on other Pseudomonas species genomes, which acts as a valuable comparative resource for P. aeruginosa research, as well as being useful for the larger Pseudomonas research community. We aim to continue to provide a central portal through which researchers may access high quality genome-associated information about P. aeruginosa and potential drug/vaccine targets, helping to accelerate research efforts to control important Pseudomonas infections.

We thank Cystic Fibrosis Foundation Therapeutics, Inc (CFFT) for critical funding support for the Pseudomonas Genome Database.


ABOUT

Database overview

Cystic Fibrosis

Pseudomonas aeruginosa

FAQs


GENOME PROJECTS

Pseudomonas
Genome Projects

Pseudomonas aeruginosa PAO1

Annotation approach
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Supplementary data
Related links

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ACKNOWLEDGEMENT

Please acknowledge use of this data and database as we describe here.