A Database of Metabolic Pathways in Pseudomonas aeruginosa PAO1

PseudoCyc was originally developed by Romero and Karp (2002) using the Pathway Tools software package.

Romero P, Karp P. PseudoCyc, a pathway-genome database for Pseudomonas aeruginosa.
J Mol Microbiol Biotechnol. 2003;5(4):230-9. (PubMed)

The annotations for P. aeruginosa PAO1 (PseudoCyc) pathways were computationally derived and subjected to manual curation by the Bioinformatics Research Group at SRI and the Pseudomonas Genome Database.


April 3, 2017

Added missing enzymes to nitrate reduction I (denitrification)

March 31, 2017

New and updated pathways

  1. Pyoverdine 1 biosynthesis
  2. Updated histidine catabolism to reflect the five-step versus four-step routes.
  3. Updated enzymes belonging to inosine-5'-phosphate biosynthesis.

Jan 23, 2017

Pathway Tools software updated from version 16.5 to 19.5 which includes improved visualization, navigation and search functionality for the website.

Imported curated pathways from MetaCyc:

  1. 2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis
  2. 4-hydroxy-2(1H)-quinolone biosynthesis
  3. alginate biosynthesis
  4. D-arginine degradation
  5. fatty acid salvage
  6. L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway)
  7. L-arginine degradation IX (arginine:pyruvate transaminase pathway)
  8. L-lyxonate degradation
  9. ornithine lipid biosynthesis
  10. putrescine degradation V
  11. pyochelin biosynthesis
  12. pyocyanin biosynthesis
  13. rhamnolipid biosynthesis
  14. salicylate biosynthesis I
  15. trans-4-hydroxy-L-proline degradation II
  16. UDP-N-acetyl-α-D-fucosamine biosynthsis

Get Started

View the PseudoCyc database featuring the Pseudomonas aeruginosa PAO1 annotation.

Compare PAO1 metabolic pathways to one or more Pseudomonas strains downloaded from the Pathway Tools website.