Pseudomonas aeruginosa PAO1, PA0285 (pipA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0071111 cyclic-guanylate-specific phosphodiesterase activity
IMP
Inferred from Mutant Phenotype
ECO:0000315
mutant phenotype evidence used in manual assertion
35638845 Reviewed by curator
Molecular Function GO:0005515 protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF08447
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00989
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Membrane proteins Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00990 Diguanylate cyclase, GGDEF domain IPR000160 GGDEF domain 331 486 7.6E-46
CDD cd00130 PAS IPR000014 PAS domain 92 195 6.31723E-11
SUPERFAMILY SSF141868 EAL domain-like IPR035919 EAL domain superfamily 506 749 2.88E-88
PANTHER PTHR44757 DIGUANYLATE CYCLASE DGCP - - 202 748 0.0
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 211 318 2.09E-29
Pfam PF00563 EAL domain IPR001633 EAL domain 507 742 5.7E-75
CDD cd01948 EAL IPR001633 EAL domain 507 747 9.91073E-115
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 87 199 3.32E-21
SMART SM00267 duf1_3 IPR000160 GGDEF domain 320 491 4.0E-61
NCBIfam TIGR00254 JCVI: diguanylate cyclase (GGDEF) domain IPR000160 GGDEF domain 327 489 6.5E-40
CDD cd01949 GGDEF IPR000160 GGDEF domain 332 489 1.15597E-62
SUPERFAMILY SSF55073 Nucleotide cyclase IPR029787 Nucleotide cyclase 336 492 1.57E-48
SMART SM00052 duf2_2 IPR001633 EAL domain 501 747 3.8E-121
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 79 197 4.3E-11
FunFam G3DSA:3.20.20.450:FF:000001 Cyclic di-GMP phosphodiesterase yahA - - 502 752 8.1E-93
SMART SM00086 pac_2 IPR001610 PAC motif 278 320 3.8E-5
Gene3D G3DSA:3.30.450.20 PAS domain - - 74 194 3.0E-36
Pfam PF00989 PAS fold IPR013767 PAS fold 209 316 1.4E-15
Pfam PF08447 PAS fold IPR013655 PAS fold-3 104 192 1.5E-21
SMART SM00086 pac_2 IPR001610 PAC motif 156 198 8.7E-10
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 209 327 5.8E-21
Gene3D G3DSA:3.30.450.20 PAS domain - - 199 324 6.6E-37
CDD cd00130 PAS IPR000014 PAS domain 215 317 9.99915E-13
FunFam G3DSA:3.30.70.270:FF:000001 Diguanylate cyclase domain protein - - 326 492 3.9E-40
SMART SM00091 pas_2 IPR000014 PAS domain 81 149 6.1E-6
SMART SM00091 pas_2 IPR000014 PAS domain 206 272 3.4E-9
Gene3D G3DSA:3.20.20.450 EAL domain IPR035919 EAL domain superfamily 502 752 1.6E-101
Gene3D G3DSA:3.30.70.270 - IPR043128 Reverse transcriptase/Diguanylate cyclase domain 325 493 2.1E-55

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.