Pseudomonas aeruginosa PAO1, PA3554 (arnA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:1901760 beta-L-Ara4N-lipid A biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 15695810 Reviewed by curator
Molecular Function GO:0016831 carboxy-lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd05257
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016742 hydroxymethyl-, formyl- and related transferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01166
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02911
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50486
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class
Adaptation, Protection Other PAO1 genes in this class
Antibiotic resistance and susceptibility Other PAO1 genes in this class
Putative enzymes Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01503 Cationic antimicrobial peptide (CAMP) resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00520 Amino sugar and nucleotide sugar metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 319 652 8.2E-71
SUPERFAMILY SSF50486 FMT C-terminal domain-like IPR011034 Formyl transferase-like, C-terminal domain superfamily 207 300 6.75E-21
Hamap MF_01166 Bifunctional polymyxin resistance protein ArnA [arnA]. IPR021168 Bifunctional polymyxin resistance protein, ArnA 3 661 61.311974
Pfam PF00551 Formyl transferase IPR002376 Formyl transferase, N-terminal 28 175 5.8E-26
CDD cd05257 Arna_like_SDR_e IPR045869 Bifunctional polymyxin resistance protein ArnA-like, extended (e) SDRs 319 650 2.15337E-117
Pfam PF01370 NAD dependent epimerase/dehydratase family IPR001509 NAD-dependent epimerase/dehydratase 320 567 1.0E-43
Gene3D G3DSA:3.40.50.720 - - - 316 659 4.8E-120
PANTHER PTHR43245 BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA - - 319 651 1.2E-84
PIRSF PIRSF036506 MtRNA_frt_NDPSE IPR021168 Bifunctional polymyxin resistance protein, ArnA 3 661 0.0
CDD cd08702 Arna_FMT_C - - 206 295 1.81339E-32
SUPERFAMILY SSF53328 Formyltransferase IPR036477 Formyl transferase, N-terminal domain superfamily 5 204 1.83E-54
FunFam G3DSA:3.40.50.720:FF:000197 Bifunctional polymyxin resistance protein ArnA - - 316 660 0.0
Pfam PF02911 Formyl transferase, C-terminal domain IPR005793 Formyl transferase, C-terminal 204 280 4.9E-16
Gene3D G3DSA:3.40.50.12230 - - - 4 295 2.4E-82

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.