Pseudomonas aeruginosa PAO1, PA0059 (osmC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0059
Name
osmC
Replicon chromosome
Genomic location 73468 - 73923 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248749.1
GI 15595257
Affymetrix PA0059_osmC_at
Entrez 878070
GenBank AAG03449.1
INSDC AAG03449.1
NCBI Locus Tag PA0059
protein_id(GenBank) gb|AAG03449.1|AE004445_10|gnl|PseudoCAP|PA0059
TIGR NTL03PA00060
UniParc UPI00000C4F0C
UniProtKB Acc Q9I773
UniProtKB ID Q9I773_PSEAE
UniRef100 UniRef100_Q9I773
UniRef50 UniRef50_P0C0L2
UniRef90 UniRef90_Q9I773

Product

Feature Type CDS
Coding Frame 1
Product Name
osmotically inducible protein OsmC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.35
Kyte-Doolittle Hydrophobicity Value -0.131
Molecular Weight (kDa) 15.6
Isoelectric Point (pI) 6.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 220 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000058 (524 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0059
Search term: osmC

Human Homologs

References

Osmotic induction of gene osmC expression in Escherichia coli K12.
Gutierrez C, Devedjian JC
J Mol Biol 1991 Aug 20;220(4):959-73
PubMed ID: 1715407
Growth-phase-dependent expression of the osmotically inducible gene osmC of Escherichia coli K-12.
Gordia S, Gutierrez C
Mol Microbiol 1996 Feb;19(4):729-36
PubMed ID: 8820643
Interplay between global regulators of Escherichia coli: effect of RpoS, Lrp and H-NS on transcription of the gene osmC.
Bouvier J, Gordia S, Kampmann G, Lange R, Hengge-Aronis R, Gutierrez C
Mol Microbiol 1998 Jun;28(5):971-80
PubMed ID: 9663683