Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0148
|
Name |
Synonym: add |
Replicon | chromosome |
Genomic location | 168213 - 169163 (+ strand) |
Transposon Mutants | 6 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_248838.1 |
GI | 15595346 |
Affymetrix | PA0148_at |
Entrez | 879249 |
GenBank | AAG03538.1 |
INSDC | AAG03538.1 |
NCBI Locus Tag | PA0148 |
protein_id(GenBank) | gb|AAG03538.1|AE004453_1|gnl|PseudoCAP|PA0148 |
TIGR | NTL03PA00149 |
UniParc | UPI0000125510 |
UniProtKB Acc | Q9I6Y4 |
UniProtKB ID | ADE_PSEAE |
UniRef100 | UniRef100_B7V265 |
UniRef50 | UniRef50_A6UXT7 |
UniRef90 | UniRef90_A6UXT7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
adenine deaminase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -14.43 |
Kyte-Doolittle Hydrophobicity Value | -0.275 |
Molecular Weight (kDa) | 36.2 |
Isoelectric Point (pI) | 4.87 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
3PAN | HYDROLASE | 10/19/10 | The crystal structure of adenosine deaminase with hypoxanthine bound from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.627 | X-RAY DIFFRACTION | 99.7 |
3OU8 | HYDROLASE | 09/14/10 | The crystal structure of adenosine deaminase from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.51 | X-RAY DIFFRACTION | 99.7 |
3PAO | HYDROLASE | 10/19/10 | The crystal structure of adenosine deaminase with adenine bound from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.493 | X-RAY DIFFRACTION | 99.7 |
3PBM | HYDROLASE | 10/20/10 | The crystal structure of adenosine deaminase in complex with chloropurine from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.591 | X-RAY DIFFRACTION | 99.7 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 254 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000146 (532 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0148
Search term: adenine deaminase
|
Ensembl
110, assembly
GRCh38.p14
|
adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186]
E-value:
1.7e-21
Percent Identity:
23.6
|
Deduced amino acid sequence of Escherichia coli adenosine deaminase reveals evolutionarily conserved amino acid residues: implications for catalytic function.
Chang ZY, Nygaard P, Chinault AC, Kellems RE
Biochemistry 1991 Feb 26;30(8):2273-80
PubMed ID: 1998686
|
Pa0148 from Pseudomonas aeruginosa catalyzes the deamination of adenine.
Goble AM, Zhang Z, Sauder JM, Burley SK, Swaminathan S, Raushel FM
Biochemistry 2011 Aug 2;50(30):6589-97
PubMed ID: 21710971
|