Pseudomonas aeruginosa PAO1, PA3560 (fruA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3560
Name
fruA
Replicon chromosome
Genomic location 3988838 - 3990595 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252250.1
GI 15598756
Affymetrix PA3560_fruA_at
Entrez 879828
GenBank AAG06948.1
INSDC AAG06948.1
NCBI Locus Tag PA3560
protein_id(GenBank) gb|AAG06948.1|AE004777_1|gnl|PseudoCAP|PA3560
TIGR NTL03PA03560
UniParc UPI00000C5A6A
UniProtKB Acc Q9HY57
UniProtKB ID Q9HY57_PSEAE
UniRef100 UniRef100_Q9HY57
UniRef50 UniRef50_A0KKR8
UniRef90 UniRef90_Q9HY57

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphotransferase system transporter fructose-specific IIBC component, FruA
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.23
Kyte-Doolittle Hydrophobicity Value 0.666
Molecular Weight (kDa) 59.0
Isoelectric Point (pI) 8.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 174 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002106 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3560
Search term: fruA

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequence of fruA, the gene specifying enzyme IIfru of the phosphoenolpyruvate-dependent sugar phosphotransferase system in Escherichia coli K12.
Prior TI, Kornberg HL
J Gen Microbiol 1988 Oct;134(10):2757-68
PubMed ID: 3076173