Pseudomonas aeruginosa PAO1, PA3562 (fruI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA3562
Name
fruI
Synonym: fruI
Synonym: ptsI
Replicon chromosome
Genomic location 3991541 - 3994411 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252252.1
GI 15598758
Affymetrix PA3562_at
Entrez 880225
GenBank AAG06950.1
INSDC AAG06950.1
NCBI Locus Tag PA3562
protein_id(GenBank) gb|AAG06950.1|AE004777_3|gnl|PseudoCAP|PA3562
TIGR NTL03PA03562
UniParc UPI00000C5A6C
UniProtKB Acc Q9HY55
UniProtKB ID Q9HY55_PSEAE
UniRef100 UniRef100_Q9HY55
UniRef50 UniRef50_E1V8C6
UniRef90 UniRef90_Q9HY55

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphotransferase system transporter enzyme I, FruI
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -32.78
Kyte-Doolittle Hydrophobicity Value -0.006
Molecular Weight (kDa) 101.6
Isoelectric Point (pI) 4.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 617 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002104 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3562
Search term: fruI

Human Homologs

References

Structure and evolution of a multidomain multiphosphoryl transfer protein. Nucleotide sequence of the fruB(HI) gene in Rhodobacter capsulatus and comparisons with homologous genes from other organisms.
Wu LF, Tomich JM, Saier MH Jr
J Mol Biol 1990 Jun 20;213(4):687-703
PubMed ID: 2193161
Discovery of a ptsHI operon, which includes a third gene (ptsT), in the thermophile Bacillus stearothermophilus.
Lai X, Ingram LO
Microbiology (Reading, Engl.) 1995 Jun;141 ( Pt 6)
PubMed ID: 7670643