Pseudomonas aeruginosa PAO1, PA3562 (fruI)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PAO1 (Stover et al., 2000) GCF_000006765.1|latest
Locus Tag	PA3562
Name	fruI Synonym: fruI Synonym: ptsI
Replicon	chromosome
Genomic location	3991541 - 3994411 (- strand)
Transposon Mutants	2 transposon mutants in PAO1
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	NP_252252.1
GI	15598758
Affymetrix	PA3562_at
Entrez	880225
GenBank	AAG06950.1
INSDC	AAG06950.1
NCBI Locus Tag	PA3562
protein_id(GenBank)	gb|AAG06950.1|AE004777_3|gnl|PseudoCAP|PA3562
TIGR	NTL03PA03562
UniParc	UPI00000C5A6C
UniProtKB Acc	Q9HY55
UniProtKB ID	Q9HY55_PSEAE
UniRef100	UniRef100_Q9HY55
UniRef50	UniRef50_E1V8C6
UniRef90	UniRef90_Q9HY55

Product

Feature Type	CDS
Coding Frame	1
Product Name	phosphotransferase system transporter enzyme I, FruI Product Name Confidence: Class 1
Synonyms
Evidence for Translation	Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7)	-32.78
Kyte-Doolittle Hydrophobicity Value	-0.006
Molecular Weight (kDa)	101.6
Isoelectric Point (pI)	4.80

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 2 Unknown (This protein may have multiple localization sites) Class 3 20472543 Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 617 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002104 (520 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA3562 Search term: fruI Search term: phosphotransferase system transporter enzyme I, FruI

Human Homologs

References

Structure and evolution of a multidomain multiphosphoryl transfer protein. Nucleotide sequence of the fruB(HI) gene in Rhodobacter capsulatus and comparisons with homologous genes from other organisms. Wu LF, Tomich JM, Saier MH Jr J Mol Biol 1990 Jun 20;213(4):687-703 PubMed ID: 2193161

Discovery of a ptsHI operon, which includes a third gene (ptsT), in the thermophile Bacillus stearothermophilus. Lai X, Ingram LO Microbiology (Reading) 1995 Jun;141 ( Pt 6):1443-1449 PubMed ID: 7670643