Pseudomonas aeruginosa PAO1, PA0023 (qor)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0023
Name
qor
Replicon chromosome
Genomic location 24568 - 25545 (- strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_248713.1
GI 15595221
Affymetrix PA0023_qor_at
Entrez 880685
GenBank AAG03413.1
INSDC AAG03413.1
NCBI Locus Tag PA0023
protein_id(GenBank) gb|AAG03413.1|AE004441_14|gnl|PseudoCAP|PA0023
TIGR NTL03PA00024
UniParc UPI0000132E62
UniProtKB Acc P43903
UniProtKB ID QOR_PSEAE
UniRef100 UniRef100_P43903
UniRef50 UniRef50_P28304
UniRef90 UniRef90_P43903

Product

Feature Type CDS
Coding Frame 1
Product Name
quinone oxidoreductase
Product Name Confidence: Class 2
Synonyms NADPH:quinone reductase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.65
Kyte-Doolittle Hydrophobicity Value -0.138
Molecular Weight (kDa) 35.1
Isoelectric Point (pI) 6.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 511 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000023 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0023
Search term: qor

Human Homologs

Ensembl 110, assembly GRCh38.p14
crystallin zeta [Source:HGNC Symbol;Acc:HGNC:2419]
E-value: 4.7e-35
Percent Identity: 29.1
Ensembl 110, assembly GRCh38.p14
crystallin zeta [Source:HGNC Symbol;Acc:HGNC:2419]
E-value: 4.7e-35
Percent Identity: 29.1

References

Crystal structure of Escherichia coli QOR quinone oxidoreductase complexed with NADPH.
Thorn JM, Barton JD, Dixon NE, Ollis DL, Edwards KJ
J Mol Biol 1995 Jun 16;249(4):785-99
PubMed ID: 7602590