Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3842
|
Name |
spcS
Synonym: orf1 |
Replicon | chromosome |
Genomic location | 4304690 - 4305040 (+ strand) |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_252531.1 |
GI | 15599037 |
Affymetrix | PA3842_at |
Entrez | 879848 |
GenBank | AAG07229.1 |
INSDC | AAG07229.1 |
NCBI Locus Tag | PA3842 |
protein_id(GenBank) | gb|AAG07229.1|AE004801_7|gnl|PseudoCAP|PA3842 |
TIGR | NTL03PA03842 |
UniParc | UPI00000D427A |
UniProtKB Acc | G3XD93 |
UniProtKB ID | G3XD93_PSEAE |
UniRef100 | UniRef100_Q51450 |
UniRef50 | UniRef50_A4STG9 |
UniRef90 | UniRef90_Q51450 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
specific Pseudomonas chaperone for ExoS, SpcS
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -7.39 |
Kyte-Doolittle Hydrophobicity Value | -0.427 |
Molecular Weight (kDa) | 13.2 |
Isoelectric Point (pI) | 4.87 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6JNP | TOXIN | 03/17/19 | Structure of ExoT-SpcS Complex from Pseudomonas aeruginosa in 2.2 Angstrom | Pseudomonas aeruginosa | 2.261 | X-RAY DIFFRACTION | 100.0 |
4JMF | TOXIN/CHAPERONE | 03/14/13 | Crystal structure of ExoT (residues 28 -77)- SpcS complex from Pseudomonas aeruginosa at 2.1 angstrom | Pseudomonas aeruginosa | 2.099 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 3 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001825 (301 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3842
Search term: spcS
Search term: specific Pseudomonas chaperone for ExoS, SpcS
|
SycE, a chaperone-like protein of Yersinia enterocolitica involved in Ohe secretion of YopE.
Wattiau P, Cornelis GR
Mol Microbiol 1993 Apr;8(1):123-31
PubMed ID: 8497188
|
Transcriptional analysis of the Pseudomonas aeruginosa exoenzyme S structural gene.
Yahr TL, Hovey AK, Kulich SM, Frank DW
J Bacteriol 1995 Mar;177(5):1169-78
PubMed ID: 7868588
|
Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III-dependent translocation induces phagocytosis resistance, cytotoxicity and disruption of actin microfilaments.
Frithz-Lindsten E, Du Y, Rosqvist R, Forsberg A
Mol Microbiol 1997 Sep;25(6):1125-39
PubMed ID: 9350868
|
Orf1/SpcS chaperones ExoS for type three secretion by Pseudomonas aeruginosa.
Shen DK, Quenee L, Bonnet M, Kuhn L, Derouazi M, Lamotte D, Toussaint B, Polack B
Biomed Environ Sci 2008 Apr;21(2):103-9
PubMed ID: 18548848
|