Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3977
|
Name |
hemL
|
Replicon | chromosome |
Genomic location | 4457362 - 4458645 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
RefSeq | NP_252666.1 |
GI | 15599172 |
Affymetrix | PA3977_hemL_at |
Entrez | 880859 |
GenBank | AAG07364.1 |
INSDC | AAG07364.1 |
NCBI Locus Tag | PA3977 |
protein_id(GenBank) | gb|AAG07364.1|AE004815_8|gnl|PseudoCAP|PA3977 |
TIGR | NTL03PA03977 |
UniParc | UPI000012BB8E |
UniProtKB Acc | P48247 |
UniProtKB ID | GSA_PSEAE |
UniRef100 | UniRef100_B7V9D9 |
UniRef50 | UniRef50_Q8X4V5 |
UniRef90 | UniRef90_Q4ZNA0 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
glutamate-1-semialdehyde 2,1-aminomutase
|
Synonyms |
glutamate-1-semialdehyde aminotransferase |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -9.26 |
Kyte-Doolittle Hydrophobicity Value | 0.099 |
Molecular Weight (kDa) | 45.4 |
Isoelectric Point (pI) | 5.57 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5I92 | ISOMERASE | 02/19/16 | Crystal structure of Glutamate-1-semialdehyde 2,1- aminomutase (GSA) from Pseudomonas aeruginosa | Pseudomonas aeruginosa | 1.75 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 638 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001704 (535 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3977
Search term: hemL
Search term: glutamate-1-semialdehyde 2,1-aminomutase
|
Cloning, mapping and characterization of the Pseudomonas aeruginosa hemL gene.
Hungerer C, Troup B, Römling U, Jahn D
Mol Gen Genet 1995 Aug 21;248(3):375-80
PubMed ID: 7565600
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|