Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4022
|
Name |
hdhA
Synonym: exaC2 |
Replicon | chromosome |
Genomic location | 4502271 - 4503791 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 3 transposon mutants in orthologs |
Comment | Part of the PA4022-eat-eutBC operon responsible for ethanolamine catabolism. |
RefSeq | NP_252711.1 |
GI | 15599217 |
Entrez | 879017 |
GenBank | AAG07409.1 |
INSDC | AAG07409.1 |
NCBI Locus Tag | PA4022 |
protein_id(GenBank) | gb|AAG07409.1|AE004819_2|gnl|PseudoCAP|PA4022 |
TIGR | NTL03PA04022 |
UniParc | UPI00000C5BC7 |
UniProtKB Acc | Q9HX05 |
UniProtKB ID | Q9HX05_PSEAE |
UniRef100 | UniRef100_U9IY98 |
UniRef50 | UniRef50_P37685 |
UniRef90 | UniRef90_A0A024HMC9 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
hydrazone dehydrogenase, HdhA
|
Synonyms | |
Evidence for Translation |
Detected using LC-MS/MS (54.98 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -9.55 |
Kyte-Doolittle Hydrophobicity Value | -0.079 |
Molecular Weight (kDa) | 55.0 |
Isoelectric Point (pI) | 5.49 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 595 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001661 (779 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4022
Search term: hdhA
Search term: hydrazone dehydrogenase, HdhA
|
Ensembl
110, assembly
GRCh38.p14
|
aldehyde dehydrogenase 2 family member [Source:HGNC Symbol;Acc:HGNC:404]
E-value:
2.3e-97
Percent Identity:
41.3
|
aldB, an RpoS-dependent gene in Escherichia coli encoding an aldehyde dehydrogenase that is repressed by Fis and activated by Crp.
Xu J, Johnson RC
J Bacteriol 1995 Jun;177(11):3166-75
PubMed ID: 7768815
|
Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation system in Pseudomonas aeruginosa: cloning and sequencing of the genes encoding cytochrome c550 and an adjacent acetaldehyde dehydrogenase.
Schobert M, Görisch H
Microbiology (Reading) 1999 Feb;145 ( Pt 2):471-481
PubMed ID: 10075429
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|
Group X aldehyde dehydrogenases of Pseudomonas aeruginosa PAO1 degrade hydrazones.
Taniyama K, Itoh H, Takuwa A, Sasaki Y, Yajima S, Toyofuku M, Nomura N, Takaya N
J Bacteriol 2012 Mar;194(6):1447-56
PubMed ID: 22267508
|
Ethanolamine Catabolism in Pseudomonas aeruginosa PAO1 Is Regulated by the Enhancer-Binding Protein EatR (PA4021) and the Alternative Sigma Factor RpoN.
Lundgren BR, Sarwar Z, Pinto A, Ganley JG, Nomura CT
J Bacteriol 2016 Sep 1;198(17):2318-29
PubMed ID: 27325678
|