Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1421
|
Name |
gbuA
Synonym: speB2 |
Replicon | chromosome |
Genomic location | 1546271 - 1547230 (- strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_250112.1 |
GI | 15596618 |
Affymetrix | PA1421_speB2_at |
DNASU | PaCD00006654 |
Entrez | 881747 |
GenBank | AAG04810.1 |
INSDC | AAG04810.1 |
NCBI Locus Tag | PA1421 |
protein_id(GenBank) | gb|AAG04810.1|AE004571_9|gnl|PseudoCAP|PA1421 |
TIGR | NTL03PA01422 |
UniParc | UPI00000C5372 |
UniProtKB Acc | Q9I3S3 |
UniProtKB ID | GBUA_PSEAE |
UniRef100 | UniRef100_Q9I3S3 |
UniRef50 | UniRef50_Q9I3S3 |
UniRef90 | UniRef90_Q9I3S3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
guanidinobutyrase
|
Synonyms |
4-guanidinobutanoate amidinohydrolase agmatinase, agmatine ureohydrolase, AUH, proclavaminate amidino hydrolase, proclavaminic acid amidino hydrolase, PAH |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -10.74 |
Kyte-Doolittle Hydrophobicity Value | -0.039 |
Molecular Weight (kDa) | 34.7 |
Isoelectric Point (pI) | 5.07 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
3NIO | HYDROLASE | 06/16/10 | Crystal structure of Pseudomonas aeruginosa guanidinobutyrase | Pseudomonas aeruginosa | 2 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 434 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001341 (475 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1421
Search term: gbuA
Search term: guanidinobutyrase
|
Ensembl
110, assembly
GRCh38.p14
|
agmatinase [Source:HGNC Symbol;Acc:HGNC:18407]
E-value:
1.2e-112
Percent Identity:
61.6
|
Purification and properties of agmatine ureohydrolyase, a putrescine biosynthetic enzyme in Escherichia coli.
Satishchandran C, Boyle SM
J Bacteriol 1986 Mar;165(3):843-8
PubMed ID: 3081491
|
Cloning, sequencing and disruption of a gene from Streptomyces clavuligerus involved in clavulanic acid biosynthesis.
Aidoo KA, Wong A, Alexander DC, Rittammer RA, Jensen SE
Gene 1994 Sep 15;147(1):41-6
PubMed ID: 8088547
|
Identification, cloning, sequencing, and overexpression of the gene encoding proclavaminate amidino hydrolase and characterization of protein function in clavulanic acid biosynthesis.
Wu TK, Busby RW, Houston TA, McIlwaine DB, Egan LA, Townsend CA
J Bacteriol 1995 Jul;177(13):3714-20
PubMed ID: 7601835
|