Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5399
|
Name |
dgcB
Synonym: dgcB |
Replicon | chromosome |
Genomic location | 6078044 - 6080005 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Strains with transposon insertions in dgcB are unable to grow on choline, glycine betaine, or dimethylglcycine but are able to utilize sarcosine. NMR analysis shows buildup of labeled dimethylglycine when dgcB mutants are given labeled choline. Predicted to function with DgcA (PA5398). |
RefSeq | NP_254086.1 |
GI | 15600592 |
Affymetrix | PA5399_at |
Entrez | 882141 |
GenBank | AAG08784.1 |
INSDC | AAG08784.1 |
NCBI Locus Tag | PA5399 |
protein_id(GenBank) | gb|AAG08784.1|AE004952_6|gnl|PseudoCAP|PA5399 |
TIGR | NTL03PA05400 |
UniParc | UPI00000C5FE4 |
UniProtKB Acc | Q9HTG5 |
UniProtKB ID | Q9HTG5_PSEAE |
UniRef100 | UniRef100_Q9HTG5 |
UniRef50 | UniRef50_Q9HTG5 |
UniRef90 | UniRef90_Q9HTG5 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
DgcB, Dimethylglycine catabolism
|
Synonyms |
DgcB, Dimethylglycine catabolism |
Evidence for Translation | |
Charge (pH 7) | 11.93 |
Kyte-Doolittle Hydrophobicity Value | 0.060 |
Molecular Weight (kDa) | 70.5 |
Isoelectric Point (pI) | 8.54 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 306 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004956 (511 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5399
Search term: dgcB
Search term: DgcB, Dimethylglycine catabolism
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism.
Wargo MJ, Szwergold BS, Hogan DA
J Bacteriol 2008 Apr;190(8):2690-9
PubMed ID: 17951379
|